# Gator Bio

> Gator Bio, founded by original BLI innovators, pioneers fast, high\-throughput Biolayer Interferometry \(BLI\) for label\-free biomolecular analysis: instruments, biosensors, and apps in antibody engineering, cell therapy, and more\.

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## Pages
- [Applications](https://www.gatorbio.com/applications/)
- [Gator Bio \| Bioprocessing Summit 2026](https://www.gatorbio.com/bioprocessing-summit-2026/)
- [Gator Bio Safety Data Sheets \(SDS\)](https://www.gatorbio.com/sds/)
- [Distributors](https://www.gatorbio.com/distributors/)
- [Request for Quote](https://www.gatorbio.com/request-for-quote/)

## Posts
- [Gator Bio Launches HIS XT Probes with AI\-Designed NovoBody™ Technology, Delivering Superior Performance for His\-Tagged Protein Analysis](https://www.gatorbio.com/news/gator-bio-launches-his-xt-probes-with-ai-designed-novobody-technology-delivering-superior-performance-for-his-tagged-protein-analysis/): Gator Bio, a pioneer in biolayer interferometry \(BLI\) technologies, has launched its new Gator HIS XT Probes—the first BLI probes to incorporate AI\-designed binding proteins\. Developed in partnership with Monod Bio, the HIS XT probes feature Monod’s proprietary NovoBody™ anti\-His binder, offering 4× higher signal resolution and 58% lower signal drift compared to traditional anti\-His sensors\. These next\-generation probes enable precise kinetic analysis, accurate quantitation, and confident detection of weak interactions, while eliminating Fc\-mediated interference common in antibody\-based assays\.

Designed for high\-throughput workflows, the HIS XT probes support both one\-step and two\-step quantitation, enabling complete characterization of 256 antibody pairs in under four hours\. Early adopters from leading biotech companies report “cleaner, more stable signals” and “superior capture performance,” confirming their value for demanding biologics and antibody engineering applications\. The HIS XT probes are available now at www\.gatorbio\.com\.
- [Gator Bio and Hudson Lab Automation Announce Proven High\-Throughput BLI Automation Solution](https://www.gatorbio.com/news/gator-bio-and-hudson-lab-automation-announce-proven-high-throughput-bli-automation-solution/): Gator Bio and Hudson Lab Automation announce a proven integrated solution for high\-throughput antibody discovery, tripling BLI assay throughput to 1,200\+ samples per day\. Showcased at SLAS 2026, the collaboration enables AI\-driven drug discovery, scalable automation, and production\-ready antibody characterization workflows\.


- [Monod Bio and Gator Bio Partner to Develop Next\-Generation Biosensors for Advanced Life Science Research](https://www.gatorbio.com/news/monod-bio-and-gator-bio-partner-to-develop-next-generation-biosensors-for-advanced-life-science-research/)

## Instruments
- [Gator Plus](https://www.gatorbio.com/instruments/gator-plus/): The Gator® Plus is a 8\-channel BLI platform that combines outstanding sensitivity, optimized for complex kinetic and quantitation assays\.
- [Gator Plus\+](https://www.gatorbio.com/instruments/gator-plus-plus/): The Gator® Plus\+  is a 8\-channel BLI platform that provides stable baselines for pM to mM affinities across a 10°C to 40°C range\. Operating as low as 10°C stabilizes sensitive proteins, captures fast kinetics, and reduces reagent evaporation\. Advanced system control minimizes baseline drift, ensuring precise analysis of delicate interactions across a wide molecular weight range\.
- [Gator Pro](https://www.gatorbio.com/instruments/gator-pro/): The Gator® Pro is a 32\-channel BLI system designed to deliver high\-throughput, high\-precision biomolecular interaction analysis for large\-scale screening and clinical development workflows\.
- [Gator Pilot](https://www.gatorbio.com/instruments/gator-pilot/): Gator® Pilot offers a cost\-effective and compact, 4\-channel BLI solution that delivers reliable performance with minimal sample volume and rapid assay turnaround\.
- [Gator Prime](https://www.gatorbio.com/instruments/gator-prime/): Gator® Prime is an 8\-channel BLI system that sets the standard for highly reliable kinetics analysis in a compact, easy\-to\-use benchtop format\. Robust engineering and proven performance for a wide range of BLI applications\.

## Applications
- [Cell \& Gene Therapy](https://www.gatorbio.com/applications/cell-and-gene-therapy/): Gator Bio’s Cell and Gene Therapy applications leverage advanced biolayer interferometry \(BLI\) technology to accelerate the development and characterization of gene therapy vectors and cell\-based therapeutics\. The platform enables real\-time, label\-free analysis of binding kinetics, affinity, and vector titers, including adeno\-associated virus \(AAV\) capsid and genome quantification\. Gator Bio's biosensors and assays support critical workflow steps such as capsid titer, empty/full particle ratio analysis, and delivery vehicle optimization\. These capabilities facilitate faster development, improved quality control, and enhanced understanding of therapeutic delivery systems essential for effective cell and gene therapies\.
- [Biologics Manufacturing](https://www.gatorbio.com/applications/manufacturing/): Gator Bio’s Manufacturing applications use their next\-generation biolayer interferometry \(BLI\) platform to optimize biotherapeutic production processes with precise, real\-time biomolecular interaction analysis\. The technology supports critical manufacturing stages including antibody titer measurements, kinetics, epitope binning, process development, and quality control\. Gator Bio’s fluidics\-free, robust instruments handle purified samples as well as complex matrices like crude extracts and serum, enabling seamless integration into manufacturing workflows\. The platform facilitates compliance with regulatory standards and accelerates process optimization, ensuring consistent, high\-quality biologics manufacturing\.
- [Antibody Engineering](https://www.gatorbio.com/applications/antibody-engineering/): Gator Bio's Antibody Engineering applications harness advanced biolayer interferometry \(BLI\) technology to accelerate the development and characterization of antibodies for diagnostics and therapeutics\. The platform provides real\-time, label\-free measurements of binding kinetics, affinity, concentration, and epitope binning with pre\-coated and customizable biosensors\. These features support comprehensive antibody characterization, including isotype profiling, glycosylation analysis, and optimization for improved function such as antibody\-drug conjugates and bispecific antibodies\. Gator Bio’s BLI solutions enable faster, more precise antibody discovery and engineering workflows, enhancing lead candidate selection and therapeutic development\.
- [Binder Discovery](https://www.gatorbio.com/applications/binder-discovery/): Gator Bio's Binder Discovery applications leverage their advanced biolayer interferometry \(BLI\) platform to accelerate the identification and characterization of binding molecules, including antibodies and other biomolecules\. The platform enables real\-time, label\-free analysis of binding kinetics, affinity, and concentration with high precision and throughput\. Precoated and customizable biosensors reduce nonspecific binding and allow analysis of a wide range of sample types, including crude and purified proteins\. This capability supports accelerated lead selection, epitope binning, and screening workflows essential for drug discovery, diagnostic development, and biomolecule engineering\. Gator Bio's BLI solutions streamline binder discovery by providing rapid, reliable data to advance therapeutics and diagnostics development efficiently\.
- [Emerging Technology](https://www.gatorbio.com/applications/emerging-technology/): Gator Bio's Emerging Technology applications showcase advanced uses of their next\-generation biolayer interferometry \(BLI\) platform for diverse innovative workflows\. This includes aptamer screening with high\-throughput, label\-free kinetic measurements; cell\-free expression analytics enabling real\-time affinity assessment directly from crude lysates; lipid nanoparticle and extracellular vesicle characterization with specialized biosensors to overcome lipid\-based binding challenges; and small molecule and peptide screening at scale with sensitive, label\-free analysis for early drug discovery\. These applications drive faster, more precise biotherapeutic development and delivery system optimization across diagnostics, synthetic biology, and next\-generation therapeutics\. The platform’s reusable sensors and versatile probes provide scalable, cost\-efficient solutions for cutting\-edge biomolecular interaction analysis\.

## Consumables
- [Regen SA \(RSA\) Kit](https://www.gatorbio.com/consumables/regen-sa-probes/)
- [Anti\-His \(HIS\) XT Probes](https://www.gatorbio.com/consumables/anti-his-his-xt-probes/)
- [Anti\-Mouse IgG Fc \(MFC\) XT Probes](https://www.gatorbio.com/consumables/anti-mouse-igg-fc-mfc-xt-probes/)
- [Picomolar \(PM\) Buffer \(1000mL\)](https://www.gatorbio.com/consumables/pm-buffer-1000ml/)
- [Picomolar \(pM\) Buffer \(50mL\)](https://www.gatorbio.com/consumables/picomolar-buffer-50ml/)

## Resources
- [Regen SA \(RSA\) Probe Information Flyer](https://www.gatorbio.com/resources/regen-sa-rsa-probe-information-flyer/)
- [Gator® Plus\+ Brochure](https://www.gatorbio.com/resources/gator-plus-brochure-2/)
- [Gator Plus\+ Information Flyer](https://www.gatorbio.com/resources/gator-plus-information-flyer/)
- [Fc Receptor Assays Using Gator Bio HIS XT Biosensors](https://www.gatorbio.com/resources/fcr-assays-his-xt-app-note/)
- [Closing the Loop SF 2026: A gathering on the AI\-native lab \- Session Recordings](https://www.gatorbio.com/resources/closing-the-loop-sf-2026-a-gathering-on-the-ai-native-lab-session-recordings/)

## Blogs
- [What does the FDA’s new biosimilars guidance actually require?](https://www.gatorbio.com/blog/what-does-the-fdas-new-biosimilars-guidance-actually-require/)
- [What is a Gator XT biosensor?](https://www.gatorbio.com/blog/what-is-a-gator-xt-biosensor/)
- [How the unrivaled Gator Plus\+ plate cooling unlocks new assay possibilities](https://www.gatorbio.com/blog/how-the-unrivaled-gator-plus-plate-cooling-unlocks-new-assay-possibilities/)
- [HIS XT Biosensor: How AI\-Designed Protein Engineering Solved the Anti\-His Baseline Drift Problem](https://www.gatorbio.com/blog/his-xt-biosensor-how-ai-designed-protein-engineering-solved-the-anti-his-baseline-drift-problem/)
- [BLI Basics \- What is BLI and How Does it Work?](https://www.gatorbio.com/blog/biolayer-interferometry-bli-basics-kinetics-quantitation/)

## Events
- [2026 ASK Summer Conference](https://www.gatorbio.com/events/ask-antibody-society-of-korea-summer-conference/)
- [2026 Colorado Protein Stability Conference](https://www.gatorbio.com/events/colorado-protein-stability-conference/)
- [ComBio Sydney 2026](https://www.gatorbio.com/events/combio-sydney-2026/)
- [2026 CABS BioPacific Conference](https://www.gatorbio.com/events/2026-cabs-biopacific-conference/)
- [The 26th Annual Meeting of the Protein Science Society of Japan \(PSSJ\)](https://www.gatorbio.com/events/protein-science-society-of-japan/)

## Galleries
- [sa\-xt\-comparison](https://www.gatorbio.com/rl_gallery/sa-xt-comparison/)
- [4x higher signal \- RSA Probes](https://www.gatorbio.com/rl_gallery/4x-higher-signal-rsa-probes/)
- [CRP/antiCRP and PD\-L1/antiPD\-L1](https://www.gatorbio.com/rl_gallery/crp-anticrp-and-pd-l1-antipd-l1/)
- [2026\-05 may blog \- erying quant analysis](https://www.gatorbio.com/rl_gallery/software-page-images-2-2-2-2-2-2-2-2-2-2-2-2/)
- [2026\-05 may blog \- vant hoff sensograms](https://www.gatorbio.com/rl_gallery/software-page-images-2-2-2-2-2-2-2-2-2-2-2/)

## Categories
- [News](https://www.gatorbio.com/category/news/)

## Document Types
- [Video](https://www.gatorbio.com/document-type/video/)
- [Poster](https://www.gatorbio.com/document-type/poster/)
- [Brochure](https://www.gatorbio.com/document-type/brochure/)
- [Application note](https://www.gatorbio.com/document-type/application-note/)
- [Ebook](https://www.gatorbio.com/document-type/ebook/)

## Application Techniques
- [Binder Discovery](https://www.gatorbio.com/resource-application-technique/binder-discovery/)
- [Antibody Engineering](https://www.gatorbio.com/resource-application-technique/antibody-engineering/)
- [Cell \& Gene Therapy](https://www.gatorbio.com/resource-application-technique/cell-gene-therapy/)
- [Biologics Manufacturing](https://www.gatorbio.com/resource-application-technique/biologics-manufacturing/)
- [Emerging Technologies](https://www.gatorbio.com/resource-application-technique/emerging-technologies/)

## Instruments
- [Gator Pro](https://www.gatorbio.com/instrument/gator-pro/)
- [Gator Pivot](https://www.gatorbio.com/instrument/gator-pivot/)
- [Gator Prime](https://www.gatorbio.com/instrument/gator-prime/)
- [Gator Pilot](https://www.gatorbio.com/instrument/gator-pilot/)
- [Gator Plus](https://www.gatorbio.com/instrument/gator-plus/)

## Product Categories
- [Biosensor](https://www.gatorbio.com/product-category/biosensor/)
- [Reagents](https://www.gatorbio.com/product-category/reagents/)
- [Plates](https://www.gatorbio.com/product-category/plates/)
- [Assay Kits](https://www.gatorbio.com/product-category/assay-kits/)
- [Software](https://www.gatorbio.com/product-category/software/)

## Application Techniques
- [Antibody Engineering](https://www.gatorbio.com/consumable-application-technique/antibody-engineering/)
- [Binder Discovery](https://www.gatorbio.com/consumable-application-technique/binder-discovery/)
- [Biologics Manufacturing](https://www.gatorbio.com/consumable-application-technique/biologics-manufacturing/)
- [Cell \& Gene Therapy](https://www.gatorbio.com/consumable-application-technique/cell-gene-therapy/)
- [Emerging Technology](https://www.gatorbio.com/consumable-application-technique/emerging-technology/)

## Application Techniques
- [Binder Discovery](https://www.gatorbio.com/blog-application-technique/binder-discovery/)
- [Cell \& Gene Therapy](https://www.gatorbio.com/blog-application-technique/cell-gene-therapy/)
- [Emerging Technologies](https://www.gatorbio.com/blog-application-technique/emerging-technologies/)
- [Antibody Engineering](https://www.gatorbio.com/blog-application-technique/antibody-engineering/)
- [Biologics Manufacturing](https://www.gatorbio.com/blog-application-technique/biologics-manufacturing/)

## Intended Uses
- [Kinetics](https://www.gatorbio.com/intended-use/kinetics/)
- [Quantitation](https://www.gatorbio.com/intended-use/quantitation/)
- [Epitope Binning](https://www.gatorbio.com/intended-use/epitope-binning/)
- [Ratio Determination](https://www.gatorbio.com/intended-use/ratio-determination/)

## Media Folders
- [probes](https://www.gatorbio.com/?taxonomy=rl_media_folder&term=probes)
- [reagents](https://www.gatorbio.com/?taxonomy=rl_media_folder&term=reagents)
- [kits](https://www.gatorbio.com/?taxonomy=rl_media_folder&term=kids)
- [release notes](https://www.gatorbio.com/?taxonomy=rl_media_folder&term=release-notes)
- [sds](https://www.gatorbio.com/?taxonomy=rl_media_folder&term=sds)

## Optional
- [Sitemap index](https://www.gatorbio.com/sitemap_index.xml)