Resources

Closing the Loop SF 2026: Designing Functional Proteins With Artificial Intelligence

Talk Title: Designing Functional Proteins With Artificial Intelligence
Event: Closing the Loop SF 2026
Recording Date: June 5, 2026
Host: Gator® Bio

Sharrol Bachas, Ph.D., Chief Scientific Officer & Co-Founder of Onava, presented this talk at Closing the Loop SF 2026, the AI protein design symposium hosted by Gator Bio. He walks through a workflow where generative models and high-throughput screening run as one loop, with each round of experimental data used to retrain the models for the next.

In this talk you will learn:

  • How an AI-human-lab-in-the-loop workflow turns protein design into an iterative engineering process
  • How quantitative screening data is featurized and used to retrain design models each round
  • Case studies where this approach rescued poor initial designs and improved developability
  • How rapid AI-lab iterations compress design-build-test cycles