Gator Anti-Mouse IgG Fc (MFC) XT Probes

For quantitation and kinetic characterization of Mouse IgG and Mouse Fc-fusion containing proteins

  • Product Number: 160049
  • Product Description: A tray of 96 Gator Anti-Mouse IgG Fc (MFC) XT probes coated with anti-Mouse specific capture ligand, for use in Q/K/QKR/EP assays
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Advancing antibody discovery

The next generation of mouse IgG analysis

Achieve faster, more accurate results with high-affinity biosensors that deliver greater binding capacity, broader detection, and cost-efficient reusability for demanding research workflows.

Gator® Bio’s new regenerable Anti-Mouse Fc (MFC) XT biosensors provide accurate quantitation and affinity characterization of anti-mouse IgG. Designed for seamless integration into antibody discovery and development workflows, they feature an enhanced design that ensures consistent performance and reproducibility.

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Binding Kinetics
Association and Dissociation Profile of Mouse PD-L1 IgG Binding to Human PD-L1

Enhanced sensitivity and dynamic range for mouse antibody screening

Gator MFC XT Biosensors are next generation anti-mouse IgG Fc capture sensors engineered for superior performance and broader dynamic range. They support both quantitation and kinetic analysis of mouse IgG antibodies and mouse Fc-fusion proteins with significantly improved sensitivity over previous MFC biosensors. 

The MFC XT sensors exhibit high affinity for all four mouse IgG subclasses (IgG1, IgG2a, IgG2b, IgG3) with minimal cross-reactivity to rat, human, and bovine IgG. They are suitable for measuring mouse IgG in both crude and purified samples. With up to a 4-fold increase in ligand binding capacity, the sensors provide enhanced kinetic characterization of small proteins and enable detection of low-abundance mouse antibodies in hybridoma cultures. 

MFC XT Biosensors can be regenerated up to 20 times with minimal loss of performance, delivering a cost-effective solution for high-throughput applications such as lead identification, hybridoma and cell line development, process optimization, and QC testing

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Faster, more accurate results with high-affinity biosensors

  • Greater binding capacity, broader dynamic range, and cost-efficient reusability for demanding research workflows
  • Rapid quantitation and kinetic analysis of crude and purified mouse IgG 
  • Wide dynamic range for fast and accurate quantitation without dilution 
  • Improved biosensor surface ligand loading capacity, delivering enhanced sensitivity for kinetics assays 
  • Robust and cost effective regeneration, enabling multiple cycles for both kinetics and quantitation applications

Key Features

MFC XT’s higher signal provides better separation, even at high concentrations

The MFC XT biosensors deliver significantly higher binding signals compared to competitor sensors, resulting in greater curve separation across a wide concentration range. This improved resolution is especially important at higher concentrations, where competitor data compresses and overlaps, making it difficult to distinguish between samples. With stronger signal and broader dynamic range, MFC XT enables more accurate quantitation and kinetic analysis, even in challenging assay conditions.

Low-End Quantitation Assay
High-End Quantitation Assay