Resources

MFC XT Biosensors for Hybridoma Screening

Download the MFC XT Biosensor for Hybridoma Screening Application Note

Hybridoma screening at scale often relies on ELISA workflows that are time-consuming and limited to endpoint data. This application note shows how MFC XT biosensors enable quantitation, off-rate ranking, and affinity-based candidate triage directly from crude supernatants in a single automated BLI run.

Inside you’ll find:

  • Single-Assay Screening: Measure titer and rank binding in one automated workflow
  • Real-Time Binding Data: Identify non-binders and weak candidates earlier
  • Wide Dynamic Range: Quantitate from 0.02 to 10,000 µg/mL without extensive dilution
  • Reliable Candidate Ranking: Use off-rate data to prioritize top clones quickly
  • Reduced Manual Work: Eliminate ELISA steps and streamline screening
  • High Throughput: Screen hundreds of clones with minimal intervention

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Resources

Optimizing BLI Assays: Effective Strategies for Reducing Non-Specific Binding

Download our new Non-Specific Binding (NSB) Application Note

Get the Complete NSB Optimization Technical Documentation

Why Download These?
Struggling with signal artifacts in complex samples?

The NSB Application Note shows you how systematic blocking strategies deliver:
✓ 90% reduction in non-specific binding
✓ 10x higher data reliability in crude lysates
✓ Accurate kinetics for low-concentration analytes
✓ Optimized protocols for BSA, detergents, and biocytin
✓ Clearer differentiation between true binding and noise

Inside you’ll find:
– Systematic NSB identification flowchart
– Step-by-step optimization protocols
– Performance data in cell culture supernatants
– Technical troubleshooting guide

Application Note Thumbnail: Optimizing BLI Assays - Effective Strategies for Reducing Non-Specific Binding (NSB)

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Resources

HIS XT Probe: Advanced His-Tag Capture for Kinetics, Quantitation, and Epitope Binning

Download our new Anti-His (HIS) XT Probes Application Note and Product Note

Get the Complete HIS XT Technical Documentation

Why Download These?
Struggling with baseline drift in His-tag assays?

The HIS XT Application Note shows you how AI-designed NovoBody™ probes deliver:
✓ 58% reduction in baseline drift
✓ 4x higher signal resolution
✓ Cleaner kinetics data for weak binders
✓ Extended probe lifetime (10+ regeneration cycles)
✓ Zero Fc interference

Inside you’ll find:
– Performance comparison data
– Application protocols (kinetics, quantitation, epitope binning)
– Customer validation results
– Technical specifications

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Resources

Characterization of Biosimilars Targeting Transmembrane Protein Variants Using Gator Biolayer Interferometry (BLI)

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PROTAC Analysis

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MFC Application Note

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Getting Started Kinetics Note

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AAVX vs Progen App Note

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Rapid Titer Measurement of AAV Vectors by AAVX Probes