gene therapy
Bioanalytical tools for AAV characterization in Gene Therapy
Adeno Associated Viruses (AAV) are one of the prime modalities to deliver genes of interest for treatment. Detailed characterization AAV capsids is critical for high efficacy and safety. Gator Bio has developed solutions to monitor some of the critical quality attributes and have ongoing research program to expand the solution offering.
Quantitation of Multiple AAV Serotypes
Quantitation of total capsids is one of the CQA monitored during each stage of AAV manufacturing. Gator Bio has developed a unique solution.
Uses CaptureSelect AAVX nanobody probe
Quantitate AAV1-10 serotypes
Accurate with wide dynamic range
Fast
Plug-n-play
Robust to various matrix used in process development and manufacturing
Cost effective with reusable probes
Webinars
Strategies for Accurate, Easy and Fast Quantitation of AAV Serotypes
Accurate High Sensitivity AAV Quantitation and Empty/Full Ratio Determination
Webinar - Evaluation of Bio Layer Interferometry (BLI) for AAV kinetics measurements
Targeted Quantitation of Different AAV Serotypes
AAV9 serotype is of great interest to researchers involved in ocular diseases. Quantitation of total capsids is one of the CQA monitored during each stage of AAV9 manufacturing. Gator Bio has developed a unique solution.
- Uses CaptureSelect AAV nanobody ligands
- Specifically quantitate AAV serotypes
- Accurate with wide dynamic range
- Fast
- Plug-n-play
- Robust to various matrix used in process development and manufacturing
- Cost effective with reusable probes
